Elite Hair Centers
We know that choosing a hair restoration provider is an important decision. At Elite Hair Centers, our unique dermatology and plastic surgery team is dedicated to delivering exceptional results with expertise and passion. This is what sets us apart from the competition.
Injectable Dutasteride/Minoxidil
Dutasteride and minoxidil, typically offered as oral and topical preparations, are now also available as intradermal injections for hair restoration. This method delivers the proven benefits of these medications while minimizing systemic side effects. Men and post-menopausal women can use a combination of dutasteride and minoxidil, while pre-menopausal women can use minoxidil alone.
Several studies have explored the effectiveness of intradermal dutasteride in treating androgenetic alopecia in men. These studies utilized concentrations of 0.05% dutasteride, 0.01% dutasteride, and 0.05% dutasteride, with injections administered at intervals ranging from weekly to every three months. Involving over 100 patients, the research revealed that 80-90% of patients experienced improvements in hair density with 0.05% and 0.01% dutasteride concentrations. However, the 0.01% concentration only showed a 30% improvement rate, indicating that this concentration is less clinically effective. Notably, adverse effects were minimal, and serum hormone levels remained unaffected, making this a suitable option for those wishing to avoid systemic side effects.
A randomized, placebo-controlled trial assessed the efficacy of a 0.5% minoxidil solution in treating female pattern hair loss in 50 patients. Injections were administered weekly for 10 weeks, with evaluations conducted six weeks after the last injection. The minoxidil group demonstrated a significant increase in the mean terminal to vellus hair ratio, while the placebo group experienced a decrease. Furthermore, 70% of patients in the minoxidil group reported perceived improvements in hair loss, compared to 37.5% in the placebo group. The only reported side effect was injection site pain. Another study evaluated a 0.05% dutasteride solution in 126 females with female pattern hair loss, finding improvement in 63% of patients.
summary
- Intradermal injections of dutasteride/minoxidil combination every month for three months, followed by injections every three to six months thereafter
- Suitable for both men and women (minoxidil alone for pre-menopausal women)
- Lower risk of systemic side effects due to the delivery method and treatment frequency
- Effective in conjunction with other treatments and beneficial for patients who did not respond well to, or cannot tolerate, topical and/or oral treatments
FAQS
What is the difference between the injectable and oral or topical formulation?
The injectable formulation allows us to deliver the medication more precisely to the hair follicle base, where it can be most effective as delivering results. Topical formulations are generally limited by absorption into the scalp. Oral formulations are quite effective, but sometimes cause other side effects.
Who is a suitable candidate for PRP hair treatment?
Men and post-menopausal women can use a combination of dutasteride and minoxidil as injections, while pre-menopausal women can use minoxidil alone. These treatments can be added onto patients who are already on oral medications as a booster, or can be used in lieu of certain oral medications if a patient has side effects.
How many sessions are needed, and how often?
The number of sessions and the frequency of treatments vary based on individual factors such as the severity of hair loss and the desired results. Typically, 3 sessions spaced at least a month apart are recommended to start, with maintenance sessions every 4-6 months advised to sustain the results over time.
Is this hair treatment painful?
Some patients may experience mild pain or discomfort during the procedure or temporary soreness afterward, but it is generally well-tolerated.
What are the potential side effects of PRP hair treatment?
Side effects are rare but may include mild swelling, redness, or bruising at the injection sites. These typically subside within a few days.
How soon can I expect to see results from PRP hair treatment?
Results can vary among individuals. Some patients may start to notice an improvement in hair quality and thickness within a few months after treatment, while others may require multiple sessions to observe noticeable changes.
TESTIMONIALS
REFERENCES
Abdallah MA, El-Zawahry KA, Besar H. Mesotherapy using dutasteride-containing solution in male pattern hair loss: A controlled pilot study. J Pan Arab Leag Dermatol. 2009;20:137–45.
Moftah N, Moftah N, Abd-Elaziz G, Ahmed N, Hamed Y, Ghannam B, et al. Mesotherapy using dutasteride-containing preparation in treatment of female pattern hair loss: Photographic, morphometric and ultrustructural evaluation. J Eur Acad Dermatol Venereol. 2013;27:686–93.
Saceda-Corralo D, Rodrigues-Barata AR, Vañó-Galván S, Jaén-Olasolo P. Mesotherapy with Dutasteride in the Treatment of Androgenetic Alopecia. Int J Trichology. 2017 Jul-Sep;9(3):143-145. doi: 10.4103/ijt.ijt_73_16. PMID: 28932074; PMCID: PMC5596657.
Sobhy N, Aly H, El Shafee A, El Deeb M. Evaluation of the effect of injection of dutasteride as mesotherapeutic tool in treatment of androgenetic alopecia in males. Our Dermatol Online. 2013;4:40–5.
Uzel BPC, Takano GHS, Chartuni JCN, Cesetti MV, Gavioli CFB, Lemes AM, Costa IMC. Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo-controlled trial. Dermatol Ther. 2021 Jan;34(1):e14622.
Before & After Gallery
*Individual results may vary.